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1

Restoration of the Activated Rig-I Pathway in Hepatitis C Virus (HCV) Replicon Cells by HCV Protease, Polymerase, and NS5A Inhibitors In Vitro at Clinically Relevant Concentrations

Kalkeri, G., Lin, C., Gopilan, J., Sloan, K., Rijnbrand, R., Kwong, A. D.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 1.84 MB

english, 2013

2

Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients

Kim, Jin Hyang, Ghosh, Alip, Ayithan, Natarajan, Romani, Sara, Khanam, Arshi, Park, Jang-June, Rijnbrand, Rene, Tang, Lydia, Sofia, Michael J., Kottilil, Shyam, Moore, Chris B., Poonia, Bhawna

Journal:

Scientific Reports

Year:

2020

Language:

english

File:

PDF, 2.60 MB

english, 2020

3

A chimeric GB virus B with 5′ nontranslated RNA sequence from hepatitis C virus causes hepatitis in tamarins

Rene Rijnbrand, Yan Yang, Lucy Beales, Francis Bodola, Kathryn Goettge, Lisette Cohen, Robert E. Lanford, Stanley M. Lemon, Annette Martin

Journal:

Year:

2005

Language:

english

File:

PDF, 571 KB

english, 2005

4

Nanoparticles, molecular biosensors, and multispectral confocal microscopy

Tarl W. Prow, Nicholas A. Kotov, Yuri M. Lvov, Rene Rijnbrand, James F. Leary

Journal:

Journal of Molecular Histology

Year:

2004

Language:

english

File:

PDF, 513 KB

english, 2004

5

Structural Requirements for Initiation of Translation by Internal Ribosome Entry within Genome-Length Hepatitis C Virus RNA

Masao Honda, Li-Hua Ping, Rene C.A. Rijnbrand, Elizabeth Amphlett, Berwyn Clarke, David Rowlands, Stanley M. Lemon

Journal:

Year:

1996

Language:

english

File:

PDF, 416 KB

english, 1996

6

The Influence of AUG Codons in the Hepatitis C Virus 5′ Nontranslated Region on Translation and Mapping of the Translation Initiation Window

René C.A. Rijnbrand, Truus E.M. Abbink, P.C.Joost Haasnoot, Willy J.M. Spaan, Peter J. Bredenbeek

Journal:

Year:

1996

Language:

english

File:

PDF, 239 KB

english, 1996

7

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus

Zihong Chen, Rene Rijnbrand, Rohit K. Jangra, Santhana G. Devaraj, Lin Qu, Yinghong Ma, Stanley M. Lemon, Kui Li

Journal:

Year:

2007

Language:

english

File:

PDF, 1.25 MB

english, 2007

8

Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

Slobodan Paessler, Rene Rijnbrand, David A. Stein, Haolin Ni, Nadezhda E. Yun, Natallia Dziuba, Viktoriya Borisevich, Alexey Seregin, Yinghong Ma, Robert Blouch, Patrick L. Iversen, Michele A. Zacks

Journal:

Year:

2008

Language:

english

File:

PDF, 1.90 MB

english, 2008

9

Antiviral activities of ISG20 in positive-strand RNA virus infections

Zhi Zhou, Nan Wang, Sara E. Woodson, Qingming Dong, Jie Wang, Yuqiong Liang, Rene Rijnbrand, Lai Wei, Joan E. Nichols, Ju-Tao Guo, Michael R. Holbrook, Stanley M. Lemon, Kui Li

Journal:

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

10

Almost the entire 5′ non-translated region of hepatitis C virus is required for cap-independent translation

René Rijnbrand, Peter Bredenbeek, Tahar van der Straaten, Linda Whetter, Geneviève Inchauspé, Stanley Lemon, Willy Spaan

Journal:

Year:

1995

Language:

english

File:

PDF, 512 KB

english, 1995

11

Mutational and Structural Analysis of Stem-loop IIIc of the Hepatitis C Virus and GB Virus B Internal Ribosome Entry Sites

Rene Rijnbrand, Varatharasa Thiviyanathan, Kumaralal Kaluarachchi, Stanley M. Lemon, David G. Gorenstein

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 708 KB

english, 2004

12

In Vitro Phenotypic Characterization of Hepatitis C Virus NS3 Protease Variants Observed in Clinical Studies of Telaprevir

Jiang, M., Mani, N., Lin, C., Ardzinski, A., Nelson, M., Reagan, D., Bartels, D., Zhou, Y., Nicolas, O., Rao, B. G., Muh, U., Hanzelka, B., Tigges, A., Rijnbrand, R., Kieffer, T. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 711 KB

english, 2013

13

1222 IN VITRO RESISTANCE TO ALS-2200, A POTENT NUCLEOTIDE POLYMERASE INHIBITOR FOR THE TREATMENT OF CHRONIC HEPATITIS C

Tan, H., Jekle, A., Kang, H., Moy, C., Deval, J., Tigges, A., Zhang, E., Jiang, M., Andzinski, A., Dyatkina, N., Wang, G., Rijnbrand, R., Kieffer, T.L., Blatt, L.M., Beigelman, L., Smith, D.B., Symons

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

14

Enhancement of the vaccinia virus/phage T7 RNA polymerase expression system using encephalomyocarditis virus 5'-untranslated region sequences

Vennema, Harry, Rijnbrand, Rene, Heijnen, Leo, Horzinek, Marian C., Spaan, Willy J.M.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.30 MB

english, 1991

15

1219 VX-135, A POTENT SINGLE DIASTEREOMER OF ALS-2200, FOR THE TREATMENT OF CHRONIC HEPATITIS C

Tan, H., Deval, J., Kang, H., Moy, C., Jin, Z., Jiang, M., Ardzinski, A., Rijnbrand, R., Kieffer, T., Blatt, L.M., Chanda, S.M., Dyatkina, N., Wang, G., Zhang, Q., Symons, J.A., Beigelman, L., Smith,

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

16

Genotypic and Phenotypic Analyses of Hepatitis C Virus Variants Observed in Clinical Studies of VX-222, a Nonnucleoside NS5B Polymerase Inhibitor

Jiang, M., Zhang, E. Z., Ardzinski, A., Tigges, A., Davis, A., Sullivan, J. C., Nelson, M., Spanks, J., Dorrian, J., Nicolas, O., Bartels, D. J., Rao, B. G., Rijnbrand, R., Kieffer, T. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 716 KB

english, 2014

17

Nonstructural Protein 5A (NS5A) and Human Replication Protein A Increase the Processivity of Hepatitis C Virus NS5B Polymerase Activity In Vitro

Mani, Nagraj, Yuzhakov, Alexander, Yuzhakov, Olga, Coll, Joyce T., Black, Jim, Saxena, Kumkum, Fulghum, John R., Lippke, Judith A., Rao, B. Govinda, Rijnbrand, Rene, Kwong, Ann D., Diamond, M. S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

18

Self-Assembly of Nucleocapsid-Like Particles from Recombinant Hepatitis C Virus Core Protein

Kunkel, M., Lorinczi, M., Rijnbrand, R., Lemon, S. M., Watowich, S. J.

Journal:

Journal of Virology

Year:

2001

Language:

english

File:

PDF, 1.47 MB

english, 2001

19

A Fluorescent Microplate Assay Quantifies Bacterial Efflux and Demonstrates Two Distinct Compound Binding Sites in AcrB

Iyer, Ramkumar, Ferrari, Annette, Rijnbrand, R., Erwin, Alice L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

20

Genetic Evidence for an Interaction between a Picornaviral cis-Acting RNA Replication Element and 3CD Protein

Yang, Y., Rijnbrand, R., Watowich, S., Lemon, S. M.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 934 KB

english, 2004

21

Mutational Analysis of the GB Virus B Internal Ribosome Entry Site

Rijnbrand, R., Abell, G., Lemon, S. M.

Journal:

Journal of Virology

Year:

2000

Language:

english

File:

PDF, 920 KB

english, 2000

22

High-resolution structure of a picornaviral internal cis-acting RNA replication element (cre)

Thiviyanathan, V., Yang, Y., Kaluarachchi, K., Rijnbrand, R., Gorenstein, D. G., Lemon, S. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 589 KB

english, 2004

23

Sequence Requirements for Viral RNA Replication and VPg Uridylylation Directed by the Internal cis-Acting Replication Element (cre) of Human Rhinovirus Type 14

Yang, Y., Rijnbrand, R., McKnight, K. L., Wimmer, E., Paul, A., Martin, A., Lemon, S. M.

Journal:

Journal of Virology

Year:

2002

Language:

english

File:

PDF, 992 KB

english, 2002

24

GB Virus B Disrupts RIG-I Signaling by NS3/4A-Mediated Cleavage of the Adaptor Protein MAVS

Chen, Z., Benureau, Y., Rijnbrand, R., Yi, J., Wang, T., Warter, L., Lanford, R. E., Weinman, S. A., Lemon, S. M., Martin, A., Li, K.

Journal:

Journal of Virology

Year:

2007

Language:

english

File:

PDF, 1018 KB

english, 2007

25

Transient Expression of Cellular Polypyrimidine-Tract Binding Protein Stimulates Cap-Independent Translation Directed by Both Picornaviral and Flaviviral Internal Ribosome Entry Sites In Vivo

Gosert, R., Chang, K. H., Rijnbrand, R., Yi, M., Sangar, D. V., Lemon, S. M.

Journal:

Molecular and Cellular Biology

Year:

2000

Language:

english

File:

PDF, 1.34 MB

english, 2000

26

Chronic hepatitis associated with GB virus B persistence in a tamarin after intrahepatic inoculation of synthetic viral RNA

Martin, A., Bodola, F., Sangar, D. V., Goettge, K., Popov, V., Rijnbrand, R., Lanford, R. E., Lemon, S. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 705 KB

english, 2003

27

Recognition of the initiation codon for protein synthesis in foot-and-mouth disease virus RNA

Thomas, A. A. M., Rijnbrand, R., Voorma, H. O.

Journal:

Journal of General Virology

Year:

1996

Language:

english

File:

PDF, 1.38 MB

english, 1996

28

A Morpholino Oligomer Targeting Highly Conserved Internal Ribosome Entry Site Sequence Is Able To Inhibit Multiple Species of Picornavirus

Stone, J. K., Rijnbrand, R., Stein, D. A., Ma, Y., Yang, Y., Iversen, P. L., Andino, R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 897 KB

english, 2008

29

Core Protein-Coding Sequence, but Not Core Protein, Modulates the Efficiency of Cap-Independent Translation Directed by the Internal Ribosome Entry Site of Hepatitis C Virus

Wang, T.-H., Rijnbrand, R. C. A., Lemon, S. M.

Journal:

Journal of Virology

Year:

2000

Language:

english

File:

PDF, 5.36 MB

english, 2000

30

Genetic Relationships and Evolution of Genotypes of Yellow Fever Virus and Other Members of the Yellow Fever Virus Group within the Flavivirus Genus Based on the 3' Noncoding Region

Mutebi, J.-P., Rijnbrand, R. C. A., Wang, H., Ryman, K. D., Wang, E., Fulop, L. D., Titball, R., Barrett, A. D. T.

Journal:

Journal of Virology

Year:

2004

Language:

english

File:

PDF, 467 KB

english, 2004

31

Size Heterogeneity in the 3' Noncoding Region of South American Isolates of Yellow Fever Virus

Bryant, J. E., Vasconcelos, P. F. C., Rijnbrand, R. C. A., Mutebi, J. P., Higgs, S., Barrett, A. D. T.

Journal:

Journal of Virology

Year:

2005

Language:

english

File:

PDF, 1.82 MB

english, 2005

32

A Novel Ranking System for Identifying Efficacious Anti-Influenza PB2 Inhibitors

Tsai, Alice W., McNeil, Colleen F., Leeman, Joshua R., Bennett, Hamilton B., Nti-Addae, Kwame, Huang, Cassey, Germann, Ursula A., Byrn, Randal A., Berlioz-Seux, Francoise, Rijnbrand, Rene, Clark, Mich

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

33

The carboxyl-terminal part of the putative Berne virus polymerase is expressed by ribosomal frameshifting and contains sequence motifs which indicate that toro- and coronaviruses are evolutionary related

Snijder, E. J., Boon, J. A.d., Bredenbeek, P. J., Horzinek, M. C., Rijnbrand, R., Spaan, W. J.M.

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 975 KB

english, 1990

34

Internal entry of ribosomes is directed by the 5' noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon

Rijnbrand, R, van der Straaten, T, van Rijn, P a, Spaan, W J, Bredenbeek, P J

Journal:

Journal of Virology

Year:

1997

Language:

english

File:

PDF, 314 KB

english, 1997

35

Antiviral Activities of ISG20

Zhou, Zhi, Wang, Nan, Woodson, Sara E, Dong, Qingming, Wang, Jie, Liang, Yuqiong, Rijnbrand, Rene, Wei, Lai, Nichols, Joan E, Guo, Ju-tao, Holbrook, Michael R, Lemon, Stanley M, Li, Kui

Year:

2012

Language:

english

File:

PDF, 2.72 MB

english, 2012

36

Inhibition of HBV replication by N-hydroxyisoquinolinedione and N-hydroxypyridinedione ribonuclease H inhibitors

Edwards, Tiffany C., Mani, Nagraj, Dorsey, Bruce, Kakarla, Ramesh, Rijnbrand, Rene, Sofia, Michael J., Tavis, John E.

Journal:

Antiviral Research

Year:

2019

File:

PDF, 1.31 MB

2019

37

Inhibition of HBV replication by N-hydroxyisoquinolinedione and N-hydroxypyridinedione ribonuclease H inhibitors

Edwards, Tiffany C., Mani, Nagraj, Dorsey, Bruce, Kakarla, Ramesh, Rijnbrand, Rene, Sofia, Michael J., Tavis, John E.

Journal:

Antiviral Research

Year:

2019

Language:

english

File:

PDF, 1.31 MB

english, 2019

38

The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs

RIJNBRAND, R., BREDENBEEK, P.J., HAASNOOT, P.C., KIEFT, J.S., SPAAN, W.J.M., LEMON, S.M.

Journal:

Year:

2001

File:

PDF, 666 KB

2001

39

Publisher Correction: Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients

Kim, Jin Hyang, Ghosh, Alip, Ayithan, Natarajan, Romani, Sara, Khanam, Arshi, Park, Jang-June, Rijnbrand, Rene, Tang, Lydia, Sofia, Michael J., Kottilil, Shyam, Moore, Chris B., Poonia, Bhawna

Journal:

Scientific Reports

Year:

2020

File:

PDF, 668 KB

2020

40

The dihydroquinolizinone compound RG7834 inhibits the polyadenylase function of PAPD5/7 and accelerates the degradation of matured HBV surface protein mRNA

Sun, Liren, Zhang, Fang, Guo, Fang, Liu, Fei, Kulsuptrakul, Jessie, Puschnik, Andreas, Gao, Min, Rijnbrand, Rene, Sofia, Michael, Block, Timothy, Zhou, Tianlun

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2020

File:

PDF, 1.52 MB

2020

41

Hepatitis B virus core protein variants observed in a first-in-human placebo-controlled study of a core protein inhibitor

Lee, Amy C.H., Thi, Emily P., Ardzinski, Andrzej, Brown, Joanne, Eley, Timothy, Mani, Nagraj, Rijnbrand, Rene, Sims, Karen, Sofia, Michael J., Picchio, Gaston

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 59 KB

2020

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